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Evolution of Stromal Resistance
Our "ELI" framework trace how stroma has evolved to regulate epithelial invasion
Dynamics in Tumor Hypoxic Response
Tumors develop hypoxia, which can also fluctuate. HIF-1a can also exhibit oscillations.
Co-opetition at Maternal Fetal Interface
MFI comprises of juxtaposed fetal and maternal tissues causing competition+co-operation
Mechanobiology and Cardiac Maturation
Cells, like all of us, live in a matrix. And the nature of the
Lab Updates
Now in Cell Systems: Cancers cells cheat in hypoxia to continue to divide
A very long collaboration that started as a side gig in my postdoc with...
Ashkan Novin is now Dr. Novin
Let us not find anyone addressing him differently. He donned the cap, and walked the extra mile.
Yasir’s work in PNAS gets featured in science media outlets
Yasir Suhail's work identifying gene regulatory basis for changes in stromal invasability across mammals
ELI work featured in The Scientist
Shawna Williams covered our joint work with Wagner lab on the connection between pregnancy
Yasir Suhail wins the K99 grant award from NIH.
Yasir Suhail received the prestigious K99/R00 award from NICHD.
Cardiac Maturation Paper now in Cell Reports
Collaborating with Junaid Afzal at UCSF, we created a platform that closely mimics the
Ashkan wins (again!) a silver in National Karate Championship in Chicago, 2021
A new theory explaining cancer metastasis in Nature EE
Our paper connecting the evolutionary connections of pregnancy and cancer metastasis. Just out in
What makes us different
People
Wenqiang Du
Post Doctoral Fellow
Yamin Liu
Post Doctoral Fellow
Yasir Suhail
Post Doctoral Fellow
Kshitiz
Principle Investigator
Kshitiz’s interest ranges largely in understanding how cells interact with their immediate microenvironment, with a particular emphasis on the mechanical and physical aspects on the microenvironment. His recent work has been focused on developing methods to create a heart tissue from human cells for drug screening, drug discovery, and tissue engineering purposes. In addition, he works on understanding the mechanisms by which stem cells and cancer cells respond to the mechanical rigidity, and topography of their milieu, in addition to the physical factors, like oxygen availability.
Ashkan Novin
Graduate Student
In Genesist, we develop a CRISPR-based therapy to empower the local and healthy cells around a tumor to prevent cancer metastasis and recurrence.
Shaofei Liu
Graduate Student
In Genesist, we develop a CRISPR-based therapy to empower the local and healthy cells around a tumor to prevent cancer metastasis and recurrence.
OUR EXPERTISE
Research Areas
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Research Tools
Our lab develops biomedical tools to specifically answer biological questions we are interested in. We have specialized assays developed in house, as well as use a variety of tools developed elsewhere, which we customize for our collaborative research.
- Secretory Dynamics Analysis Platform
- Bioinformatics Methods
- Cancer Invasion Assay
- Traction Force Microscopy
- Capillary Force Lithography
