Kshitiz’s interest ranges largely in understanding how cells interact with their immediate microenvironment, with a particular emphasis on the mechanical and physical aspects on the microenvironment. His recent work has been focused on developing methods to create a heart tissue from human cells for drug screening, drug discovery, and tissue engineering purposes. In addition, he works on understanding the mechanisms by which stem cells and cancer cells respond to the mechanical rigidity, and topography of their milieu, in addition to the physical factors, like oxygen availability.
In Genesist, we develop a CRISPR-based therapy to empower the local and healthy cells around a tumor to prevent cancer metastasis and recurrence.
In Genesist, we develop a CRISPR-based therapy to empower the local and healthy cells around a tumor to prevent cancer metastasis and recurrence.
Our lab develops biomedical tools to specifically answer biological questions we are interested in. We have specialized assays developed in house, as well as use a variety of tools developed elsewhere, which we customize for our collaborative research.