# Corresponding Authors, * Authors contributed equally
47. Kshitiz±, Afzal J, Suhail Y, Chang H, Hubbi ME, Hamidzadeh A, Goyal R, Liu Y, Sun P, Dang CV±, Levchenko A± (2022), Lactate-dependent chaperone-mediated autophagy induces oscillatory HIF-1a activity promoting proliferation of hypoxic cells, Cell Systems, Accepted. ±: Corresponding Authors Article
46. Menon N, Suhail Y, Goyal R, Du W, Tanguay AP, Jay GD, Ghosh M, Kshitiz±, Schmidt T± (2022). Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells, IJMS, 23(21), 12711. ±: Corresponding Authors. Article
45. Afzal J±, Du W, Novin A, Liu Y, Wali K, Murthy A, Garen A, Wagner G, Kshitiz± (2022), Paracrine HB-EGF signaling reduce enhanced contractile and energetic state of activated decidual fibroblasts by rebalancing SRF-MRTF-TCF transcriptional axis, Frontiers in Cell and Development Biology, 10, 927361. ±: Corresponding Authors Article
44. Afzal J±, Liu Y, Du W*, Suhail Y*, Zong P, Feng J, Ajeti V, Sayyad WA, Nikolaus J, Yankova M, Deymier AC, Yue L, Kshitiz±, Cardiac ultrastructure inspired matrix induces advanced metabolic and functional maturation of differentiated human cardiomyocytes, Cell Reports, 40, 111146. ±: Corresponding Authors Article
43. Suhail Y, Maziarz J.D., Novin A, Dighe A, Afzal J, Wagner G, Kshitiz (2022). Tracing the cis-regulatory changes underlying the endometrial control of placental invasion, Proceedings of the National Academy of Sciences, 119(6). Article
42. Liu S, Suhail Y, Novin A, Perpetua L, Kshitiz (2022). Metastatic transition of pancreatic ductal cell adenocarcinoma is accompanied by the emergence of pro-invasive cancer associated fibroblasts, Cancers, 14(9), 2197. Article
41. Ma X, Dighe A, Maziarz J, Neumann E, Erkenbrack E, Hei YY, Liu Y, Suhail Y, Kshitiz, Pak I, Levchenko A, Wagner GP (2022). Evolution of higher mesenchymal CD44 expression in the human lineage: a gene linked to cancer malignancy, Evolution, Medicine, and Public Health, 10(1), 447-462. Article
40. Wang L, Wang B, Gasek NS, Zhou Y, Zhou Y, Cohn RL, Martin DE, Zuo W, Flynn WF, Guo C, Jellison ER, Kin T, Prata LGPL, Palner AK, Li M, Inman CL, Barber LS, Al-Naggar IMA, Zhou Y, Du W, Kshitiz, Kuchel GA, Meves A, Tchknonia T, Kirkland JL, Robson P, Xu M (2022). Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity, Cell Metabolism, 34, 75-89. Article
39. Wagner GP±, Kshitiz, Dighe A, Levchenko A (2021). The Coevolution of Placentation and Cancer, Annual Review of Animal Biosciences, 10, 259-279. Article
38. Suhail Y, Afzal J, Kshitiz (2021). Evolved Resistance to Placental Invasion Secondarily Confers Increased Survival in Melanoma Patients, Journal of Clinical Medicine, 10(595). Article
37. Suhail Y, Afzal J, Kshitiz (2021). Incorporating and addressing testing bias within estimates of epidemic dynamics for SARS-Cov-2, BMC Medical Research Methodology, 21(1). Article
36. Novin A, Suhail Y, Ajeti V, Goyal R, Wali K, Seck A, Jackson A, Kshitiz (2021). Diversity in cancer invasion phenotypes indicates specific stroma regulated programs, Human Cell, 34(1), 111-121. Article
35. Chiou G, Jui E, Rhea AC, Gorthi A, Miar S, Acosta FM, Perez C, Suhail Y, Kshitiz, Chen Y, Ong JL, Bizios R, Rathbone C, Guda T (2020). Scaffold Architecture and Matrix Strain Modulate Mesenchymal Cell and Microvascular Growth and Development in a Time Dependent Manner, Cellular and Molecular Bioengineering, 13, 507-526. Article
34. Wagner G, Kshitiz, Levchenko A (2020). Comments on Boddy et al., 2020: Available data suggests positive relationship between placental invasion and malignancy, Evolution, Medicine, & Public Health, 1, 211-214. Article
33. Suhail Y, Upadhyay M, Chhibber A, Kshitiz (2020). Machine Learning for the Diagnosis of Orthodontic Extractions: A Computational Analysis Using Ensemble Learning, Bioengineering, 7(2), 55. Article
32. Gassaway BM, Cardone RL, Padyana AK, Petersen MC, Judd ET, Hayes S, Tong S, Barber KW, Apostolidi M, Abulizi A, Sheetz JB, Kshitiz, Aerni HR, Gross S, Kung C, Samuel VT, Shulman GI, Kibbey RG, Rinehart J (2019). Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production, Cell Reports, 29(11), 3394-3404. Article
31. Kshitiz±, Afzal J, Maziarz JD, Hamidzadeh A, Liang C, Erkenbrack EM, Ham H, Haeger, JD, Pfarrer C, Hoang T, Ott T, Spencer T, Pavlicev M, Antczak D, Levchenko A±, Wagner GP± (2019). The Evolution of Plancental Invasion and Cancer Metastasis are Causally Linked, Nature Ecology and Evolution 3, 1743-1753. ±: Corresponding Authors. Article
30. Yasir Suhail, Margo P. Cain, Kiran Vanaja, Paul A. Kurywchak, Andre Levchenko, Raghu Kalluri, Kshitiz# (2019), Systems Biology of Cancer Metastasis, Cell Systems, 9(2), 109-127. Article
29. Kshitiz#*, Ellison DD*, Suhail Y*, Afzal J, Woo L, Kilic O, Spees J, Levchenko A# (2019). Dynamic secretome of bone marrow-derived stromal cells reveals a cardioprotective biochemical cocktail, Proceedings of the National Academy of Sciences USA. Article
28. Park JS, Kim DH, Shah SR, Kim HN, Kshitiz, Kim P, Quinones-Hinojosa A, Levchenko A (2019), Switch-like enhancement of epithelial-mesenchymal transition by YAP through feedback regulation of WT1 and Rho-family GTPases, Nature Communications, 2797. Article
27. Kshitiz#, Afzal J, Hamidzadeh A, Chang H, Hubbi ME, Suhail Y, Goyal R, Sun P, Nicoli S, Dang CV#, Levchenko A# (2019). Lactate-Dependent Chaperone-Mediated Autophagy Induces Oscillatory HIF-1 alpha Activity Promoting Proliferation of Hypoxic Cells, CELL-D-19-01403 (in review). Article
26. Kim DH, Ewald AJ, Park JS, Kshitiz, Kwark M, Gray RS, Su CY, Seo J, An SS, Levchenko A (2018). Biomechanical interplay between anisotropic re-organization of cells and the surrounding matrix underlies transition to invasive cancer spread, Scientific Reports, 14210. Article
25. Ahn EH#, Lee MB, Seo DJ, Lee J, Kim Y, Kshitiz (2018). Sphingosine Induces Apoptosis and Down-regulation of MYCN in PAX3-FOXO1 positive Alveolar Rhabdomyosarcoma Cells Irrespective of TP53 Mutation, Anticancer Research, 38(1), 71-76. Article
24. Kshitiz, Afzal J, Chang H, Goyal R, Levchenko A (2016). Mechanics of Microenvironment as Instructive Cues Guiding Stem Cell Behavior, Current Stem Cell Reports, 2(1), 62-72. Article
23. Kshitiz, Afzal J*, Suhail Y*, Ahn EH, Goyal R, Hubbi ME, Hussaini Q, Ellison DD, Goyal J, Nacev B, Kim DH, Lee JH, Frankel S, Gray K, Bankoti R, Chien AJ, Levchenko A (2015). Control of the interface between heterotypic cell populations reveals the mechanism of intercellular transfer of signaling proteins, Integrative Biology, 7, 364-372. Article
22. Kshitiz, Afzal J, Kim SY, Kim DH (2014). A nanotopography approach for studying the structure-function relationship of cells and tissues, Cell Adhesion & Migration, 8(4). Article
21. Hubbi ME, Gilkes DM, Hu H, Kshitiz, Ahmed I, Semenza GL (2014). Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1α to promote cell-cycle progression Supporting Information, Proceedings of the National Academy of Sciences (Accepted). Article
20. Kshitiz, Afzal J, Kim DH, Levchenko A (2014). Mechanotransduction via p190RhoGAP regulates a switch between cardiomyogenic and endothelial lineages in adult cardiac progenitors, Stem Cells, 32(8), 1999-2007. Article19. Ahn EH*, Kim Y*, Kshitiz*, An SS, Afzal J, Lee S, Kwak M, Suh KY, Kim DH, Levchenko A (2014). Spatial control of stem cell fate using nanotopographic cues, Biomaterials, 35(8), 2401-2410. Article
18. Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL, (2013). Sirtuin-7 Inhibits the Activity of Hypoxia-Inducible Factors, Journal of Biological Chemistry, 288, 20768-775. Article
17. Kshitiz, Afzal J, Kim SY, Kim DH, (2014). A nanotopography approach for studying the structure-function relationships of cells and tissues, Cell Adhesion and Migration, 8(4). Article
16. Hubbi ME, Hu H, Kshitiz, Ahmed I, Levchenko A, Semenza GL (2013). Chaperone-mediated autophagy targets HIF-1a for lysosomal degradation, Journal of Cell Biology, (Accepted). Article
15. Hubbi ME*, Kshitiz*, Gilkes DM, Rey S, Wong CC, Luo W, Kim DH, Dang CV, Levchenko A, Semenza GL (2013). A non-transcriptional role for HIF-1a as a direct inhibitor of DNA replication, Science Signaling, vol. 6, pp. ra10. (Featured as a Cover Article). Article Podcast
14. Suhail Y*, Kshitiz*, Lee J, Walker M, Kim DH, Brennan MD, Bader JS, Levchenko A (2013). Modeling intercellular transfer of biomolecules through tunneling nanotubes, Bulletin of Mathematical Biology, 75(8), 1400-1416. Article
13. Chaturvedi P, Gilkes DM, Wong CC, Kshitiz, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. (2013). Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis, Journal of Clinical Investigations, 123(1):189-205. Article
12. Kshitiz*, Hubbi ME*, Ahn EH, Downey J, Kim DH, Rey S, Kundu A, Semenza GL, Abraham RM, Levchenko, A. (2012). Matrix rigidity coordinates the proliferation, differentiation, and morphogenesis of endothelial cells derived from cardiac progenitors, Science Signaling, 5(227):ra41. (Featured as a Article, Highlighted in Science). Article
11. Kim DH*, Kshitiz*, Smith R, Kim P, Marban E, Suh KY, Levchenko A. (2012). Nanopatterned Cardiac Cell Patches Promote Stem Cell Niche Formation and Myocardial Regeneration, Integrative Biology, 4(9):1019-33. (Featured as a Cover Article). Article
10. Kshitiz, Park JS, Kim P, Helen W, Engler AJ, Levchenko A, Kim DH. (2012). Control of stem cell fate and function by engineering physical microenvironment, Integrative Biology, 4:1008-18. Article
9. Berman SMC, Kshitiz, Wang JC, Orukari I, Levchenko A, Bulte JWM, Walczak P. (2012). Cell motility of neural stem cells is reduced after SPIO-labeling, which is mitigated after exocytosis, Magnetic Resonance in Imaging, doi: 10.1002/mrm.24216. Article
8. Bankoti R, Gupta K, Levchenko A, Stager S. (2012). Marginal zone B-cells regulate antigen-specific T-cell responses during infection, Journal of Immunology, 188:3961-71. Article
7. Kshitiz, Kim DH, Beebe D, Levchenko A. (2011). Micro- and nanoengineering for stem cell biology: the promise with a caution, Trends in Biotechnology, 29(8):399-408. Article
6. Gupta K, Kim DH, Ellison D, Smith C, Kundu A, Tuan J, Suh KY, Levchenko A. (2011). Lab-on- a-chip devices as an emerging platform for stem cell biology, Lab on a Chip, 10(16):2019-31. Article
5. Rey S, Lee K, Wang CJ, Gupta K, Chen S, McMillan A, Bhise N, Levchenko A, Semenza GL. (2009). Synergistic effect of HIF-1alpha gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia, Proc Natl Acad Sci USA. 106(48):20399-404. Article
3. Niu X, Gupta K, Yang JT, Shamblott MJ, Levchenko A. (2009). Physical transfer of membrane and cytoplasmic components as a general mechanism of cell-cell communication, Journal of Cell Science, 122(Pt 5):600-610. Article
2. Gupta K*, Sehgal V*, Levchenko A. (2008). A method for probabilistic mapping between protein structure and function taxonomies through cross training, BMC Structural Biology, 8:40. Article
